Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM33048
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
2820±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM33048
Synonyms:
(5Z)-5-{[4-(dimethylamino)phenyl]imino}-1-(3-hydroxypropyl)-4-methyl-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-2,6-diketo-4-methyl-nicotinonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-4-methyl-2,6-dioxo-3-pyridinecarbonitrile | 5-[4-(dimethylamino)phenyl]imino-1-(3-hydroxypropyl)-4-methyl-2,6-dioxopyridine-3-carbonitrile | 5-[4-(dimethylamino)phenyl]imino-4-methyl-2,6-bis(oxidanylidene)-1-(3-oxidanylpropyl)pyridine-3-carbonitrile | MLS000089998 | SMR000024616 | cid_3239318
Type:
Small organic molecule
Emp. Form.:
C18H20N4O3
Mol. Mass.:
340.3764
SMILES:
CN(C)c1ccc(cc1)\N=C1/C(C)=C(C#N)C(=O)N(CCCO)C1=O |t:13|
Structure:
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