Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM32283
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
2550±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM32283
Synonyms:
2-[[2-amino-1-(3-methoxypropyl)pyrrolo[3,2-b]quinoxaline-3-carbonyl]amino]-4,5,6,7-tetrahydrobenzothiophene-3-carboxylic acid methyl ester | 2-[[[2-amino-1-(3-methoxypropyl)-3-pyrrolo[3,2-b]quinoxalinyl]-oxomethyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid methyl ester | 2-{[2-Amino-1-(3-methoxy-propyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carbonyl]-amino}-4,5,6,7-tetrahydro-b enzo[b]thiophene-3-carboxylic acid methyl ester | MLS000595323 | SMR000149846 | cid_1930463 | methyl 2-[[2-amino-1-(3-methoxypropyl)pyrrolo[3,2-b]quinoxaline-3-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate | methyl 2-[[2-azanyl-1-(3-methoxypropyl)pyrrolo[3,2-b]quinoxalin-3-yl]carbonylamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C25H27N5O4S
Mol. Mass.:
493.578
SMILES:
COCCCn1c(N)c(C(=O)Nc2sc3CCCCc3c2C(=O)OC)c2nc3ccccc3nc12
Structure:
Search PDB for entries with ligand similarity: