Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM32294
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
2520±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM32294
Synonyms:
(1,1-diketo-1,2-benzothiazol-3-yl)-methyl-[[(E)-3-phenylprop-2-enylidene]amino]amine | (1E,2E)-3-phenylacrylaldehyde (1,1-dioxido-1,2-benzisothiazol-3-yl)(methyl)hydrazone | MLS000585612 | N-methyl-1,1-bis(oxidanylidene)-N-[[(E)-3-phenylprop-2-enylidene]amino]-1,2-benzothiazol-3-amine | N-methyl-1,1-dioxo-N-[[(E)-3-phenylprop-2-enylidene]amino]-1,2-benzothiazol-3-amine | SMR000207593 | cid_12004606
Type:
Small organic molecule
Emp. Form.:
C17H15N3O2S
Mol. Mass.:
325.385
SMILES:
CN(N=C\C=C\c1ccccc1)C1=NS(=O)(=O)c2ccccc12 |w:2.1,t:13|
Structure:
Search PDB for entries with ligand similarity: