Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 1
Ligand
BDBM32304
Substrate
n/a
Meas. Tech.
Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer)
EC50
29800±n/a nM
Citation
 PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays (HPSMTB buffer) PubChem Bioassay (2008)[AID] 
Target
Name:
Glutathione S-transferase Mu 1
Synonyms:
GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:
PROTEIN
Mol. Mass.:
25712.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799596
Residue:
218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
  
Inhibitor
Name:
BDBM32304
Synonyms:
6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-dione | 6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-quinone | MLS000723361 | SMR000236434 | cid_2892892
Type:
Small organic molecule
Emp. Form.:
C22H17NO4
Mol. Mass.:
359.3747
SMILES:
COc1ccc(OC)c(c1)-n1c(=O)c2ccccc2c2ccccc2c1=O |(8.56,6.3,;7.89,4.91,;8.76,3.64,;10.29,3.75,;11.16,2.48,;10.49,1.09,;11.36,-.18,;12.9,-.07,;8.96,.98,;8.09,2.25,;8.29,-.41,;9.25,-1.62,;10.75,-1.27,;8.91,-3.12,;10.25,-4,;10.14,-5.6,;8.69,-6.3,;7.38,-5.38,;7.52,-3.78,;6.13,-3.12,;4.97,-4.23,;3.44,-3.76,;3.08,-2.2,;4.26,-1.12,;5.79,-1.62,;6.75,-.41,;6.08,.98,)|
Structure:
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