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Target
Bcl-2-like protein 2
Ligand
BDBM33107
Substrate
n/a
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W.
EC50
170±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33107
Synonyms:
2-chloranyl-3-[[4-(diethylamino)phenyl]amino]naphthalene-1,4-dione | 2-chloro-3-[4-(diethylamino)anilino]-1,4-naphthoquinone | 2-chloro-3-[4-(diethylamino)anilino]naphthalene-1,4-dione | 2-chloro-3-{[4-(diethylamino)phenyl]amino}naphthoquinone | MLS000595078 | SMR000184814 | cid_1380424
Type:
Small organic molecule
Emp. Form.:
C20H19ClN2O2
Mol. Mass.:
354.83
SMILES:
CCN(CC)c1ccc(NC2=C(Cl)C(=O)c3ccccc3C2=O)cc1 |c:10|
Structure:
Search PDB for entries with ligand similarity: