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TargetAlkaline phosphatase, tissue-nonspecific isozyme
LigandBDBM51396
Substrate/Competitorn/a
Meas. Tech.SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay
EC50 7790±n/a nM
Citation PubChem, PC SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Alkaline phosphatase, tissue-nonspecific isozyme
Name:Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:tissue-nonspecific alkaline phosphatase precursor
Type:PROTEIN
Mol. Mass.:57306.17
Organism:Homo sapiens
Description:ChEMBL_1448917
Residue:524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD
GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG
VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH
SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE
KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN
RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG
QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG
YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV
PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM51396
NameBDBM51396
Synonyms:3-cyclohexyl-N-(1H-1,2,4-triazol-5-yl)propanamide | 3-cyclohexyl-N-(1H-1,2,4-triazol-5-yl)propionamide | MLS-0026826.0001 | cid_803937
TypeSmall organic molecule
Emp. Form.C11H18N4O
Mol. Mass.222.2868
SMILESO=C(CCC1CCCCC1)Nc1nnc[nH]1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a