Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM52007
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase
IC50
748±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM52007
Synonyms:
(5-nitro-2-phenyl-phenyl)arsonic acid | (5-nitro-2-phenylphenyl)arsonic acid | MLS000756422 | SMR000528721 | cid_302501
Type:
Small organic molecule
Emp. Form.:
C12H10AsNO5
Mol. Mass.:
323.1331
SMILES:
O[As](O)(=O)c1cc(ccc1-c1ccccc1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: