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Target
Beta-lactamase
Ligand
BDBM52011
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
1310±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM52011
Synonyms:
4-cyclohexyl-3-(2-thienyl)-1H-1,2,4-triazole-5-thione | 4-cyclohexyl-3-thiophen-2-yl-1H-1,2,4-triazole-5-thione | 4-cyclohexyl-5-(2-thienyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione | MLS000858937 | SMR000459016 | cid_2816425
Type:
Small organic molecule
Emp. Form.:
C12H15N3S2
Mol. Mass.:
265.398
SMILES:
S=c1[nH]nc(-c2cccs2)n1C1CCCCC1
Structure:
Search PDB for entries with ligand similarity: