Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52477
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52477
Synonyms:
5-[2,5-dimethyl-3-[2-[2-(tosylamino)acetyl]oxyacetyl]pyrrol-1-yl]benzene-1,3-dicarboxylic acid dimethyl ester | 5-[2,5-dimethyl-3-[2-[2-[(4-methylphenyl)sulfonylamino]-1-oxoethoxy]-1-oxoethyl]-1-pyrrolyl]benzene-1,3-dicarboxylic acid dimethyl ester | MLS000393629 | SMR000247859 | cid_3494085 | dimethyl 5-[2,5-dimethyl-3-[2-[2-[(4-methylphenyl)sulfonylamino]acetyl]oxyacetyl]pyrrol-1-yl]benzene-1,3-dicarboxylate | dimethyl 5-[2,5-dimethyl-3-[2-[2-[(4-methylphenyl)sulfonylamino]ethanoyloxy]ethanoyl]pyrrol-1-yl]benzene-1,3-dicarboxylate
Type:
Small organic molecule
Emp. Form.:
C27H28N2O9S
Mol. Mass.:
556.584
SMILES:
COC(=O)c1cc(cc(c1)-n1c(C)cc(C(=O)COC(=O)CNS(=O)(=O)c2ccc(C)cc2)c1C)C(=O)OC
Structure:
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