Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM43035
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
38930±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM43035
Synonyms:
2,3-Dihydro-benzo[1,4]dioxine-6-carboxylic acid (2-naphthalen-2-yl-benzooxazol-5-yl)-amide | MLS000558441 | N-(2-naphthalen-2-yl-1,3-benzoxazol-5-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide | N-[2-(2-naphthalenyl)-1,3-benzoxazol-5-yl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide | N-[2-(2-naphthyl)-1,3-benzoxazol-5-yl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide | SMR000148957 | cid_4378441
Type:
Small organic molecule
Emp. Form.:
C26H18N2O4
Mol. Mass.:
422.4321
SMILES:
O=C(Nc1ccc2oc(nc2c1)-c1ccc2ccccc2c1)c1ccc2OCCOc2c1
Structure:
Search PDB for entries with ligand similarity: