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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM50526
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
4110±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM50526
Synonyms:
2-thioxodihydropyrimidine-4,5,6(1H)-trione 5-[(3-nitro-1,1'-biphenyl-4-yl)hydrazone] | 5-[(2-nitro-4-phenyl-phenyl)hydrazinylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione | 5-[(2-nitro-4-phenyl-phenyl)hydrazono]-2-thioxo-hexahydropyrimidine-4,6-quinone | 5-[(2-nitro-4-phenylphenyl)hydrazinylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione | MLS000719967 | SMR000304496 | cid_6255619
Type:
Small organic molecule
Emp. Form.:
C16H11N5O4S
Mol. Mass.:
369.355
SMILES:
[O-][N+](=O)c1cc(ccc1[NH+]=N[c-]1c(=O)[nH]c(=S)[nH]c1=O)-c1ccccc1 |w:9.9|
Structure:
Search PDB for entries with ligand similarity: