Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM54678
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM54678
Synonyms:
(3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylidene)-1H-indol-2-one | (3E)-7-bromo-3-(1-ketoindan-2-ylidene)oxindole | (3E)-7-bromo-3-(3-oxo-1H-inden-2-ylidene)-1H-indol-2-one | UNM-0000305764 | cid_25220925
Type:
Small organic molecule
Emp. Form.:
C17H10BrNO2
Mol. Mass.:
340.171
SMILES:
Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O
Structure:
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