Reaction Details Report a problem with these data
Target
Ras-related protein Rab-2A
Ligand
BDBM54590
Substrate
n/a
Meas. Tech.
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
Ki
60±n/a nM
Comments
Extracted from aid = 2045 and tid = 5
Citation
 PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2016)[AID] 
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Canis lupus familiaris
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
  
Inhibitor
Name:
BDBM54590
Synonyms:
1-(3-fluorophenyl)-3,5-bis(4-methoxyphenyl)-2-pyrazoline | 2-(3-fluorophenyl)-3,5-bis(4-methoxyphenyl)-3,4-dihydropyrazole | UNM-0000305828 | cid_2827701
Type:
Small organic molecule
Emp. Form.:
C23H21FN2O2
Mol. Mass.:
376.4234
SMILES:
COc1ccc(cc1)C1CC(=NN1c1cccc(F)c1)c1ccc(OC)cc1 |c:11|
Structure:
Search PDB for entries with ligand similarity: