Reaction Details Report a problem with these data
Target
Streptokinase A
Ligand
BDBM58064
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58064
Synonyms:
(2S)-2-bromo-N-(2,3-dichlorophenyl)-3-keto-4,7,7-trimethyl-norbornane-1-carboxamide | (3S)-3-bromo-N-(2,3-dichlorophenyl)-1,7,7-trimethyl-2-oxo-4-bicyclo[2.2.1]heptanecarboxamide | (3S)-3-bromo-N-(2,3-dichlorophenyl)-1,7,7-trimethyl-2-oxobicyclo[2.2.1]heptane-4-carboxamide | (3S)-N-[2,3-bis(chloranyl)phenyl]-3-bromanyl-1,7,7-trimethyl-2-oxidanylidene-bicyclo[2.2.1]heptane-4-carboxamide | 2-Bromo-4,7,7-trimethyl-3-oxo-bicyclo[2.2.1]heptane-1-carboxylic acid (2,3-dichloro-phenyl)-amide | MLS000768761 | SMR000432106 | cid_16682217
Type:
Small organic molecule
Emp. Form.:
C17H18BrCl2NO2
Mol. Mass.:
419.14
SMILES:
CC1(C)C2(C)CCC1([C@H](Br)C2=O)C(=O)Nc1cccc(Cl)c1Cl |TLB:11:10:1:6.5,THB:9:8:1:6.5|
Structure:
Search PDB for entries with ligand similarity: