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Target
Streptokinase A
Ligand
BDBM58087
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58087
Synonyms:
2-Cyclohexyl-3-(4-methoxy-benzyl)-10-methyl-3H,10H-pyrimido[4,5-b]quinoline-4,5-dione | 2-cyclohexyl-10-methyl-3-p-anisyl-pyrimido[4,5-b]quinoline-4,5-quinone | 2-cyclohexyl-3-[(4-methoxyphenyl)methyl]-10-methyl-pyrimido[4,5-b]quinoline-4,5-dione | 2-cyclohexyl-3-[(4-methoxyphenyl)methyl]-10-methylpyrimido[4,5-b]quinoline-4,5-dione | MLS000763169 | SMR000439510 | cid_2028520
Type:
Small organic molecule
Emp. Form.:
C26H27N3O3
Mol. Mass.:
429.5109
SMILES:
COc1ccc(Cn2c(nc3n(C)c4ccccc4c(=O)c3c2=O)C2CCCCC2)cc1
Structure:
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