Reaction Details Report a problem with these data
Target
Heat shock factor protein 1
Ligand
BDBM63390
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)
EC50
>195000±0 nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM63390
Synonyms:
2-[4-cyclopentyl-1-(1-isopropyl-4-piperidyl)piperazin-2-yl]ethanol | 2-[4-cyclopentyl-1-(1-isopropylpiperidin-4-yl)piperazin-2-yl]ethanol | 2-[4-cyclopentyl-1-(1-propan-2-yl-4-piperidinyl)-2-piperazinyl]ethanol | 2-[4-cyclopentyl-1-(1-propan-2-ylpiperidin-4-yl)piperazin-2-yl]ethanol | MLS000734593 | SMR000317823 | cid_16187348
Type:
Small organic molecule
Emp. Form.:
C19H37N3O
Mol. Mass.:
323.5166
SMILES:
CC(C)N1CCC(CC1)N1CCN(CC1CCO)C1CCCC1
Structure:
Search PDB for entries with ligand similarity: