Target
Mu-type opioid receptor
Ligand
BDBM62190
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the MOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM62190
Synonyms:
4-[[(4-acetylphenyl)sulfonylamino]methyl]-N-[2-(3-fluoroanilino)-2-keto-ethyl]-N-methyl-benzamide | 4-[[(4-acetylphenyl)sulfonylamino]methyl]-N-[2-(3-fluoroanilino)-2-oxoethyl]-N-methylbenzamide | 4-[[(4-ethanoylphenyl)sulfonylamino]methyl]-N-[2-[(3-fluorophenyl)amino]-2-oxidanylidene-ethyl]-N-methyl-benzamide | MLS-0332830.0001 | cid_16295215
Type:
Small organic molecule
Emp. Form.:
C25H24FN3O5S
Mol. Mass.:
497.539
SMILES:
CN(CC(=O)Nc1cccc(F)c1)C(=O)c1ccc(CNS(=O)(=O)c2ccc(cc2)C(C)=O)cc1
Structure:
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