Reaction Details Report a problem with these data
Target
General amino acid permease AGP1
Ligand
BDBM66027
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hits
EC50
3845±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hits PubChem Bioassay (2010)[AID] 
Target
Name:
General amino acid permease AGP1
Synonyms:
AGP1 | AGP1_YEAST | Agp1p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
69674.09
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_85666113
Residue:
633
Sequence:
MSSSKSLYELKDLKNSSTEIHATGQDNEIEYFETGSNDRPSSQPHLGYEQHNTSAVRRFFDSFKRADQGPQDEVEATQMNDLTSAISPSSRQAQELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTALVHAGPAGLLIGYAIMGSILYCIIQACGEMALVYSNLTGGYNAYPSFLVDDGFGFAVAWVYCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVIIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFNGKHAIDRFKGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLATIILLGFLVPYNSDQLLGSTGGGTKASPYVIAVASHGVRVVPHFINAVILLSVLSMANSSFYSSARLFLTLSEQGYAPKVFSYIDRAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLAISGLSQLFTWTAICLSHLRFRRAMKVQGRSLGELGFKSQTGVWGSAYACIMMILILIAQFWVAIAPIGEGKLDAQAFFENYLAMPILIALYVGYKVWHKDWKLFIRADKIDLDSHRQIFDEELIKQEDEEYRERLRNGPYWKRVVAFWC
  
Inhibitor
Name:
BDBM66027
Synonyms:
(4-bromophenyl)-[4-(4-methoxy-2-nitro-phenyl)piperazin-1-yl]methanone | (4-bromophenyl)-[4-(4-methoxy-2-nitro-phenyl)piperazino]methanone | (4-bromophenyl)-[4-(4-methoxy-2-nitrophenyl)-1-piperazinyl]methanone | (4-bromophenyl)-[4-(4-methoxy-2-nitrophenyl)piperazin-1-yl]methanone | 1-(4-bromobenzoyl)-4-(4-methoxy-2-nitrophenyl)piperazine | MLS000672486 | SMR000296120 | cid_2973383
Type:
Small organic molecule
Emp. Form.:
C18H18BrN3O4
Mol. Mass.:
420.257
SMILES:
COc1ccc(N2CCN(CC2)C(=O)c2ccc(Br)cc2)c(c1)[N+]([O-])=O
Structure:
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