Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM67043
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM67043
Synonyms:
(5R)-5-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]-1-cyclohex-2-enone | (5R)-5-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phenyl]cyclohex-2-en-1-one | MLS002472169 | SMR001395320 | cid_44144093
Type:
Small organic molecule
Emp. Form.:
C20H17F3O2
Mol. Mass.:
346.343
SMILES:
COc1ccc(cc1)[C@H]1CC(=O)C=C(C1)c1ccccc1C(F)(F)F |c:13|
Structure:
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