Reaction Details Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM67048
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
>350000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID] 
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM67048
Synonyms:
MLS002245115 | N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-5-(2-furanylmethylsulfamoyl)-2-methylbenzamide | N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-5-(2-furfurylsulfamoyl)-2-methyl-benzamide | N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-5-(furan-2-ylmethylsulfamoyl)-2-methyl-benzamide | N-[2-(dimethylamino)-2-(4-methoxyphenyl)ethyl]-5-(furan-2-ylmethylsulfamoyl)-2-methylbenzamide | SMR001308780 | cid_16290431
Type:
Small organic molecule
Emp. Form.:
C24H29N3O5S
Mol. Mass.:
471.569
SMILES:
COc1ccc(cc1)C(CNC(=O)c1cc(ccc1C)S(=O)(=O)NCc1ccco1)N(C)C
Structure:
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