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Target
Serine/threonine-protein kinase 33
Ligand
BDBM67636
Substrate
n/a
Meas. Tech.
Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity
EC50
86050±n/a nM
Citation
 PubChem, PC Luminescence Cell-Free Homogenous Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein kinase 33
Synonyms:
STK33 | STK33_HUMAN | Serine/threonine-protein kinase 33
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57833.21
Organism:
Homo sapiens (Human)
Description:
gi_23943882
Residue:
514
Sequence:
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAEIKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
  
Inhibitor
Name:
BDBM67636
Synonyms:
5-bromanyl-3-(4-methoxyphenyl)-7-methyl-7-oxidanyl-isochromene-6,8-dione | 5-bromo-7-hydroxy-3-(4-methoxyphenyl)-7-methyl-2-benzopyran-6,8-dione | 5-bromo-7-hydroxy-3-(4-methoxyphenyl)-7-methyl-isochromene-6,8-quinone | 5-bromo-7-hydroxy-3-(4-methoxyphenyl)-7-methylisochromene-6,8-dione | CMLD003390 | MLS000438321 | SMR000452554 | cid_16745544
Type:
Small organic molecule
Emp. Form.:
C17H13BrO5
Mol. Mass.:
377.186
SMILES:
COc1ccc(cc1)C1=CC2=C(Br)C(=O)C(C)(O)C(=O)C2=CO1 |c:11,22,t:9|
Structure:
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