Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM68019
Substrate
n/a
Meas. Tech.
Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress
IC50
>10000±n/a nM
Citation
 PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay (2010)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM68019
Synonyms:
2-Chloro-3-phenylamino-[1,4]naphthoquinone | 2-anilino-3-chloro-1,4-naphthoquinone | 2-anilino-3-chloronaphthalene-1,4-dione | 2-chloranyl-3-phenylazanyl-naphthalene-1,4-dione | MLS000588884 | SMR000212533 | cid_14161
Type:
Small organic molecule
Emp. Form.:
C16H10ClNO2
Mol. Mass.:
283.709
SMILES:
ClC1=C(Nc2ccccc2)C(=O)c2ccccc2C1=O |c:1|
Structure:
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