Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM68317
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 4
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM68317
Synonyms:
3-[4-(3-chlorophenyl)piperazin-1-yl]carbonyl-N,N-dimethyl-4-pyrrolidin-1-yl-benzenesulfonamide | 3-[4-(3-chlorophenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidin-1-ylbenzenesulfonamide | 3-[4-(3-chlorophenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidino-benzenesulfonamide | 3-[[4-(3-chlorophenyl)-1-piperazinyl]-oxomethyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide | MLS-0435543.0001 | cid_24982085
Type:
Small organic molecule
Emp. Form.:
C23H29ClN4O3S
Mol. Mass.:
477.019
SMILES:
CN(C)S(=O)(=O)c1ccc(N2CCCC2)c(c1)C(=O)N1CCN(CC1)c1cccc(Cl)c1
Structure:
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