Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM68309
Substrate
n/a
Meas. Tech.
SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 3
IC50
7680±n/a nM
Citation
 PubChem, PC SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM68309
Synonyms:
MLS-0435535.0001 | N-(2-methoxy-5-morpholin-4-ylsulfonyl-phenyl)-5-methyl-4-propyl-thiophene-2-carboxamide | N-(2-methoxy-5-morpholin-4-ylsulfonylphenyl)-5-methyl-4-propylthiophene-2-carboxamide | N-(2-methoxy-5-morpholinosulfonyl-phenyl)-5-methyl-4-propyl-thiophene-2-carboxamide | N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]-5-methyl-4-propyl-2-thiophenecarboxamide | cid_16279444
Type:
Small organic molecule
Emp. Form.:
C20H26N2O5S2
Mol. Mass.:
438.561
SMILES:
CCCc1cc(sc1C)C(=O)Nc1cc(ccc1OC)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: