Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM68322
Substrate
n/a
Meas. Tech.
SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 3
IC50
20300±n/a nM
Citation
 PubChem, PC SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM68322
Synonyms:
4-(3,5-dimethyl-1-pyrazolyl)-N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]benzamide | 4-(3,5-dimethylpyrazol-1-yl)-N-(2-methoxy-5-morpholin-4-ylsulfonyl-phenyl)benzamide | 4-(3,5-dimethylpyrazol-1-yl)-N-(2-methoxy-5-morpholin-4-ylsulfonylphenyl)benzamide | 4-(3,5-dimethylpyrazol-1-yl)-N-(2-methoxy-5-morpholinosulfonyl-phenyl)benzamide | MLS-0311344.0001 | cid_3538139
Type:
Small organic molecule
Emp. Form.:
C23H26N4O5S
Mol. Mass.:
470.541
SMILES:
COc1ccc(cc1NC(=O)c1ccc(cc1)-n1nc(C)cc1C)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: