Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM75990
Substrate
n/a
Meas. Tech.
Dose Response Confirmation of compounds that inhibit VHR1 in Fluorescent Assay
IC50
8430±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of compounds that inhibit VHR1 in Fluorescent Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM75990
Synonyms:
MLS000765462 | N-(2-pyridin-3-yl-1,3-benzoxazol-5-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide | N-[2-(3-pyridinyl)-1,3-benzoxazol-5-yl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide | N-[2-(3-pyridyl)-1,3-benzoxazol-5-yl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide | SMR000289567 | cid_1160074
Type:
Small organic molecule
Emp. Form.:
C21H15N3O4
Mol. Mass.:
373.3615
SMILES:
O=C(Nc1ccc2oc(nc2c1)-c1cccnc1)c1ccc2OCCOc2c1
Structure:
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