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Target
Sentrin-specific protease 8
Ligand
BDBM76483
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM76483
Synonyms:
MLS000335917 | SMR000253671 | [2-(7-ethyl-1H-indol-3-yl)-2-oxidanylidene-ethyl] benzoate | [2-(7-ethyl-1H-indol-3-yl)-2-oxoethyl] benzoate | benzoic acid [2-(7-ethyl-1H-indol-3-yl)-2-keto-ethyl] ester | benzoic acid [2-(7-ethyl-1H-indol-3-yl)-2-oxoethyl] ester | cid_2125022
Type:
Small organic molecule
Emp. Form.:
C19H17NO3
Mol. Mass.:
307.3432
SMILES:
CCc1cccc2c(c[nH]c12)C(=O)COC(=O)c1ccccc1
Structure:
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