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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM76336
Substrate
n/a
Meas. Tech.
Dose Response confirmation of compounds that inhibit HePTP
IC50
1520±n/a nM
Citation
 PubChem, PC Dose Response confirmation of compounds that inhibit HePTP PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM76336
Synonyms:
6-bromanyl-2-pyridin-2-yl-N-pyridin-4-yl-quinoline-4-carboxamide | 6-bromo-2-(2-pyridinyl)-N-4-pyridinyl-4-quinolinecarboxamide | 6-bromo-2-(2-pyridinyl)-N-pyridin-4-yl-4-quinolinecarboxamide | 6-bromo-2-(2-pyridyl)-N-(4-pyridyl)cinchoninamide | 6-bromo-2-pyridin-2-yl-N-pyridin-4-ylquinoline-4-carboxamide | MLS000672592 | SMR000295450 | cid_1261644
Type:
Small organic molecule
Emp. Form.:
C20H13BrN4O
Mol. Mass.:
405.247
SMILES:
Brc1ccc2nc(cc(C(=O)Nc3ccncc3)c2c1)-c1ccccn1
Structure:
Search PDB for entries with ligand similarity: