Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM54145
Substrate
n/a
Meas. Tech.
Dose Response confirmation of compounds that inhibit HePTP
IC50
3280±n/a nM
Citation
 PubChem, PC Dose Response confirmation of compounds that inhibit HePTP PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM54145
Synonyms:
5-[[3-(1,3-benzothiazol-2-yl)-4-methyl-2-thienyl]amino]-5-keto-valeric acid | 5-[[3-(1,3-benzothiazol-2-yl)-4-methyl-2-thiophenyl]amino]-5-oxopentanoic acid | 5-[[3-(1,3-benzothiazol-2-yl)-4-methyl-thiophen-2-yl]amino]-5-oxidanylidene-pentanoic acid | 5-[[3-(1,3-benzothiazol-2-yl)-4-methylthiophen-2-yl]amino]-5-oxopentanoic acid | 5-{[3-(1,3-benzothiazol-2-yl)-4-methyl-2-thienyl]amino}-5-oxopentanoic acid | MLS000850222 | SMR000456240 | cid_2811901
Type:
Small organic molecule
Emp. Form.:
C17H16N2O3S2
Mol. Mass.:
360.451
SMILES:
Cc1csc(NC(=O)CCCC(O)=O)c1-c1nc2ccccc2s1
Structure:
Search PDB for entries with ligand similarity: