Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM42373
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay
IC50
17200±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM42373
Synonyms:
MLS000091923 | N-[3-[butyl(ethyl)amino]propyl]-7-methoxy-2-furo[2,3-b]quinolinecarboxamide | N-[3-[butyl(ethyl)amino]propyl]-7-methoxy-furo[2,3-b]quinoline-2-carboxamide | N-[3-[butyl(ethyl)amino]propyl]-7-methoxyfuro[2,3-b]quinoline-2-carboxamide | N-{3-[butyl(ethyl)amino]propyl}-7-methoxyfuro[2,3-b]quinoline-2-carboxamide | SMR000026447 | cid_3245431
Type:
Small organic molecule
Emp. Form.:
C22H29N3O3
Mol. Mass.:
383.484
SMILES:
CCCCN(CC)CCCNC(=O)c1cc2cc3ccc(OC)cc3nc2o1
Structure:
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