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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78543
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
1545±104 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78543
Synonyms:
MLS000087827 | N-(2-methyl-4-oxidanylidene-quinazolin-3-yl)-4-propoxy-benzamide | N-(2-methyl-4-oxo-3-quinazolinyl)-4-propoxybenzamide | N-(2-methyl-4-oxoquinazolin-3(4H)-yl)-4-propoxybenzamide | N-(2-methyl-4-oxoquinazolin-3-yl)-4-propoxybenzamide | N-(4-keto-2-methyl-quinazolin-3-yl)-4-propoxy-benzamide | SMR000024047 | cid_3237593
Type:
Small organic molecule
Emp. Form.:
C19H19N3O3
Mol. Mass.:
337.3725
SMILES:
CCCOc1ccc(cc1)C(=O)Nn1c(C)nc2ccccc2c1=O
Structure:
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