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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78626
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
1332±89 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78626
Synonyms:
2-Amino-4-methyl-thiazole-5-carboxylic acid (1H-indol-3-ylmethylene)-hydrazide | 2-amino-N'-[(Z)-3-indolylidenemethyl]-4-methyl-5-thiazolecarbohydrazide | 2-amino-N'-[(Z)-indol-3-ylidenemethyl]-4-methyl-1,3-thiazole-5-carbohydrazide | 2-amino-N'-[(Z)-indol-3-ylidenemethyl]-4-methyl-thiazole-5-carbohydrazide | 2-azanyl-N'-[(Z)-indol-3-ylidenemethyl]-4-methyl-1,3-thiazole-5-carbohydrazide | MLS000525734 | SMR000116208 | cid_6537515
Type:
Small organic molecule
Emp. Form.:
C14H13N5OS
Mol. Mass.:
299.351
SMILES:
Cc1nc(N)sc1C(=O)NN=Cc1c[nH]c2ccccc12 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: