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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM59086
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
1977±103 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM59086
Synonyms:
1-[N'-[6-[[amino-[[N'-(2-ethylhexyl)amidino]amino]methylene]amino]hexyl]amidino]-2-(2-ethylhexyl)guanidine;hydrochloride | 1-[N'-[6-[[amino-[[N'-(2-ethylhexyl)carbamimidoyl]amino]methylidene]amino]hexyl]carbamimidoyl]-2-(2-ethylhexyl)guanidine;hydrochloride | 1-[N'-[6-[[azanyl-[[N'-(2-ethylhexyl)carbamimidoyl]amino]methylidene]amino]hexyl]carbamimidoyl]-2-(2-ethylhexyl)guanidine;hydrochloride | 1-[amino-[6-[[amino-[[amino(2-ethylhexylimino)methyl]amino]methylidene]amino]hexylimino]methyl]-2-(2-ethylhexyl)guanidine;hydrochloride | Alexidine dihydrochloride | MLS002153995 | SMR001233329 | cid_18968508
Type:
Small organic molecule
Emp. Form.:
C26H56N10
Mol. Mass.:
508.7898
SMILES:
CCCCC(CC)CN=C(N)NC(N)=NCCCCCCN=C(N)NC(N)=NCC(CC)CCCC |w:27.27,8.7,14.14,21.20|
Structure:
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