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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM50073568
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
873±24 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM50073568
Synonyms:
6,7-Dimethoxy-2-piperazin-1-yl-quinazolin-4-ylamine | Aminodimethoxyquinazolinylpiperazine (piperazine derivative of terazosin) | CHEMBL1226 | cid_616267
Type:
Small organic molecule
Emp. Form.:
C14H19N5O2
Mol. Mass.:
289.333
SMILES:
COc1cc2nc(nc(N)c2cc1OC)N1CCNCC1
Structure:
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