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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM72267
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
594±135 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM72267
Synonyms:
1-(3-methylphenyl)-3-[(2-oxidanylideneindol-3-yl)amino]thiourea | 1-(3-methylphenyl)-3-[(2-oxo-3-indolyl)amino]thiourea | 1-(3-methylphenyl)-3-[(2-oxoindol-3-yl)amino]thiourea | 1-[(2-ketoindol-3-yl)amino]-3-(m-tolyl)thiourea | 1H-indole-2,3-dione 3-[N-(3-methylphenyl)thiosemicarbazone] | MLS000705089 | SMR000231438 | cid_5465946
Type:
Small organic molecule
Emp. Form.:
C16H14N4OS
Mol. Mass.:
310.374
SMILES:
Cc1cccc(NC(=S)NNC2=c3ccccc3=NC2=O)c1 |c:11,18|
Structure:
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