Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM79428
Substrate
n/a
Meas. Tech.
Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7
EC50
>85267±n/a nM
Citation
 PubChem, PC Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 PubChem Bioassay (2011)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM79428
Synonyms:
2-(1,3-benzodioxol-5-yl)-3-hydroxy-1-benzopyran-4-one | 2-(1,3-benzodioxol-5-yl)-3-hydroxy-chromone | 2-(1,3-benzodioxol-5-yl)-3-hydroxychromen-4-one | 2-(1,3-benzodioxol-5-yl)-3-oxidanyl-chromen-4-one | 2-Benzo[1,3]dioxol-5-yl-3-hydroxy-chromen-4-one | MLS000026972 | SMR000009557 | cid_624794
Type:
Small organic molecule
Emp. Form.:
C16H10O5
Mol. Mass.:
282.2476
SMILES:
Oc1c(oc2ccccc2c1=O)-c1ccc2OCOc2c1
Structure:
Search PDB for entries with ligand similarity: