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Target
Caspase-7
Ligand
BDBM79430
Substrate
n/a
Meas. Tech.
Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7
EC50
>85261±n/a nM
Citation
 PubChem, PC Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 PubChem Bioassay (2011)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM79430
Synonyms:
3-[2-[4-(dimethylamino)phenyl]-2-keto-ethyl]-6,7-dimethoxy-phthalide | 3-[2-[4-(dimethylamino)phenyl]-2-oxidanylidene-ethyl]-6,7-dimethoxy-3H-2-benzofuran-1-one | 3-[2-[4-(dimethylamino)phenyl]-2-oxoethyl]-6,7-dimethoxy-3H-2-benzofuran-1-one | 3-[2-[4-(dimethylamino)phenyl]-2-oxoethyl]-6,7-dimethoxy-3H-isobenzofuran-1-one | MLS000108118 | SMR000104080 | cid_2864745
Type:
Small organic molecule
Emp. Form.:
C20H21NO5
Mol. Mass.:
355.3844
SMILES:
COc1ccc2C(CC(=O)c3ccc(cc3)N(C)C)OC(=O)c2c1OC
Structure:
Search PDB for entries with ligand similarity: