Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM71650
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
1210±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2011)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM71650
Synonyms:
2,5-Dibutyl-benzene-1,3-diol | 2,5-dibutylbenzene-1,3-diol | 2,5-dibutylresorcinol | MLS000030857 | SMR000009083 | cid_651512
Type:
Small organic molecule
Emp. Form.:
C14H22O2
Mol. Mass.:
222.3233
SMILES:
CCCCc1cc(O)c(CCCC)c(O)c1
Structure:
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