BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Targetputative hexokinase HKDC1
LigandBDBM80783
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of activators of hexokinase domain containing I (HKDC1)
EC50 11500±n/a nM
Citation PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
putative hexokinase HKDC1
Name:putative hexokinase HKDC1
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:102520.24
Organism:Homo sapiens (Human)
Description:gi_156151420
Residue:917
Sequence:
MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM80783
NameBDBM80783
Synonyms:3,5-Dimethoxy-N-[N'-(pyrazine-2-carbonyl)-hydrazinocarbothioyl]-benzamide | 3,5-dimethoxy-N-[(pyrazin-2-ylcarbonylamino)carbamothioyl]benzamide | 3,5-dimethoxy-N-[(pyrazine-2-carbonylamino)carbamothioyl]benzamide | 3,5-dimethoxy-N-[(pyrazinoylamino)thiocarbamoyl]benzamide | 3,5-dimethoxy-N-[[[oxo(2-pyrazinyl)methyl]hydrazo]-sulfanylidenemethyl]benzamide | MLS000590712 | SMR000219116 | cid_1881906
TypeSmall organic molecule
Emp. Form.C15H15N5O4S
Mol. Mass.361.376
SMILESCOc1cc(OC)cc(c1)C(=O)NC(=S)NNC(=O)c1cnccn1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a