Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 2
Ligand
BDBM81518
Substrate
n/a
Ki
293±n/a nM
Comments
PDSP_498
Citation
 Jackson, RH; Morrissey, MM; Sills, MA; Jarvis, MF Comparison of antagonist and agonist binding to the leukotriene B4 receptor intact human polymorphonuclear neutrophils (PMN). J Pharmacol Exp Ther 262:80-9 (1992) [PubMed] 
Target
Name:
Leukotriene B4 receptor 2
Synonyms:
BLT2R | BLTR2 | LT4R2_HUMAN | LTB4 receptor JULF2 | LTB4-R 2 | LTB4-R2 | LTB4R2 | LTB4R2 protein | Leukotriene B4 | Leukotriene B4 R2 | Leukotriene B4 receptor | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | Leukotriene b1 | Seven transmembrane receptor BLTR2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37964.86
Organism:
Homo sapiens (Human)
Description:
Leukotriene 2 0 HUMAN::Q9NPC1
Residue:
358
Sequence:
MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
  
Inhibitor
Name:
BDBM81518
Synonyms:
CGS 23167
Type:
Small organic molecule
Emp. Form.:
C18H26N4O3
Mol. Mass.:
346.424
SMILES:
CCc1cc(C(C)=O)c(O)cc1OCCCCC(C)(C)c1nnn[nH]1
Structure:
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