Reaction Details
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Pituitary adenylate cyclase-activating polypeptide
Ligand
BDBM81531
Substrate
n/a
Ki
10±n/a nM
Comments
PDSP_2356
Citation
Robberecht, P; Gourlet, P; De Neef, P; Woussen-Colle, MC; Vandermeers-Piret, MC; Vandermeers, A; Christophe, J Structural requirements for the occupancy of pituitary adenylate-cyclase-activating-peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB-OK-1 cell membranes. Discovery of PACAP(6-38) as a potent antagonist. Eur J Biochem 207:239-46 (1992) [PubMed] Article More Info.:
Target
Name:
Pituitary adenylate cyclase-activating polypeptide
Synonyms:
ADCYAP1 | PACAP | PACA_HUMAN | Pituitary adenylate cyclase-activating polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18847.28
Organism:
Homo sapiens (Human)
Description:
PACAP 0 HUMAN::P18509
Residue:
176
Sequence:
MTMCSGARLALLVYGIIMHSSVYSSPAAAGLRFPGIRPEEEAYGEDGNPLPDFDGSEPPGAGSPASAPRAAAAWYRPAGRRDVAHGILNEAYRKVLDQLSAGKHLQSLVARGVGGSLGGGAGDDAEPLSKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL
Inhibitor
Name:
BDBM81531
Synonyms:
[D-Phe2]PACAP-38 | [DPhe2]PACAP(1-38)
Type:
Small organic molecule
Emp. Form.:
C209H335N63O52S
Mol. Mass.:
4594.352
SMILES:
n/a
Structure:
