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Target
Protachykinin-1
Ligand
BDBM50010685
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_664
Citation
 Mottola, DM; Brewster, WK; Cook, LL; Nichols, DE; Mailman, RB Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist. J Pharmacol Exp Ther 262:383-93 (1992) [PubMed] 
Target
Name:
Protachykinin-1
Synonyms:
Nka | Nkna | Protachykinin-1 | Substance K | Substance P | TKN1_RAT | Tac1 | Tac2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15007.06
Organism:
RAT
Description:
Substance K 0 RAT::P06767
Residue:
130
Sequence:
MKILVAVAVFFLVSTQLFAEEIGANDDLNYWSDWSDSDQIKEAMPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRRK
  
Inhibitor
Name:
BDBM50010685
Synonyms:
(+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine | (6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | CHEMBL43345 | Dihydrexidine, DHX
Type:
Small organic molecule
Emp. Form.:
C17H17NO2
Mol. Mass.:
267.3224
SMILES:
Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O
Structure:
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