Reaction Details
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Report a problem with these dataTarget
Alpha-2C adrenergic receptor
Ligand
BDBM50017452
Substrate
n/a
Ki
126±n/a nM
Comments
PDSP_1045
Citation
Blaxall, HS; Murphy, TJ; Baker, JC; Ray, C; Bylund, DB Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line. J Pharmacol Exp Ther 259:323-9 (1991) [PubMed] More Info.:
Target
Name:
Alpha-2C adrenergic receptor
Synonyms:
ADRA2C | adrenergic Alpha2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27257.01
Organism:
OK
Description:
adrenergic Alpha2C ADRA2C OK::G3GWB4
Residue:
230
Sequence:
MAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRSDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCKSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
Inhibitor
Name:
BDBM50017452
Synonyms:
2-chloro-6-piperazin-1-ylpyrazine | 6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl | 6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl(MK-212) | CHEMBL269521 | L-630,571 | MK 212 | MK-212
Type:
Small organic molecule
Emp. Form.:
C8H11ClN4
Mol. Mass.:
198.653
SMILES:
Clc1cncc(n1)N1CCNCC1
Structure:
