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TargetADRA2C
LigandBDBM50020192
Substrate/Competitorn/a
Ki 0.67±n/a nM
CommentsPDSP_1743
Citation Blaxall, HSMurphy, TJBaker, JCRay, CBylund, DB Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line. J Pharmacol Exp Ther259:323-9 (1991) [PubMed]
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ADRA2C
Name:ADRA2C
Synonyms:Alpha-2C adrenergic receptor | adrenergic Alpha2C
Type:Enzyme Catalytic Domain
Mol. Mass.:53254.77
Organism:OPOSSUM
Description:adrenergic Alpha2C ADRA2C OPOSSUM::P35405
Residue:469
Sequence:
MDLQLTTNSTDSGDRGGSSNESLQRQPPSQYSPAEVAGLAAVVSFLIVFTIVGNVLVVIA
VLTSRALKAPQNLFQVSLASADILVATLVMPFSLANELMNYWYFGKVWCVIYLALDVLFC
TSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRIKGIIVTVWLISAVISFPPLISLYRDPE
DDLYPQCELNDETWYILSSCIGSFFAPCIIMVLVYVRIYRVAKLRTRTLSEKRTVPEGSS
QTENGLSRPPVGAGPSTAAAAAASLRLQAGENGHYHLHHHHHHLHHHHHHHHHQLRKSAE
LEDIELEESSTSENRRRRRSREEAAARKGSRGFSFSFSSTKGGQSAGAGSRLSRASNRSL
EFFSTHRRRKRSSLCRRKVTQAREKRFTFVLAVVMGVFVVCWFPFFFTYSLYGICREACQ
VPETLFKFFFWIGYCNSSLNPVIYTIFNQDFRRSFKHILFKKKKKTSLQ
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  Blast E-value cutoff:
BDBM50020192
NameBDBM50020192
Synonyms:8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | CHEMBL300555 | Spiroxatrine
TypeSmall organic molecule
Emp. Form.C22H25N3O3
Mol. Mass.379.4522
SMILESO=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1
Structure
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n/a