Target
Beta-arrestin-2
Ligand
BDBM50136166
Substrate
n/a
Ki
3630.78±n/a nM
Comments
PDSP_832
Citation
 Wong, DTThrelkeld, PGRobertson, DW Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors. Neuropsychopharmacology 5:43-7 (1991) [PubMed] 
Target
Name:
Beta-arrestin-2
Synonyms:
5-HT2C | ARRB2 | ARRB2_BOVIN | Beta-arrestin-2 | HTR2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47232.00
Organism:
Beef
Description:
5-HT2C HTR2C Beef::P32120
Residue:
420
Sequence:
MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIALPRPQSAATHPPTLLPSAVPETDAPVDTNLIEFETNYATDDDIVFEDFARLRLKGLKDEDYDDQFC
  
Inhibitor
Name:
BDBM50136166
Synonyms:
(3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine | (R)-fluoxetine | CHEMBL153036 | FLUOXETINE | Methyl-[(R)-3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine | Methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine
Type:
Small organic molecule
Emp. Form.:
C17H18F3NO
Mol. Mass.:
309.3261
SMILES:
CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1 |r|
Structure:
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