Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50240370
Substrate
n/a
Ki
173.78±n/a nM
Comments
PDSP_1427
Citation
 Tsuchihashi, H; Nakashima, Y; Kinami, J; Nagatomo, T Characteristics of 125I-iodocyanopindolol binding to beta-adrenergic and serotonin-1B receptors of rat brain: selectivity of beta-adrenergic agents. Jpn J Pharmacol 52:195-200 (1990) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rattus norvegicus (Rat)
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM50240370
Synonyms:
1-(2-(allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol (Oxprenolol) | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol(oxprenolol) | CHEMBL546 | OXPRENOLOL | Trasicor
Type:
Small organic molecule
Emp. Form.:
C15H23NO3
Mol. Mass.:
265.348
SMILES:
CC(C)NCC(O)COc1ccccc1OCC=C
Structure:
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