Reaction Details Report a problem with these data
Target
Beta-1 adrenergic receptor
Ligand
BDBM50240370
Substrate
n/a
Ki
7.76±n/a nM
Comments
PDSP_1427
Citation
 Tsuchihashi, H; Nakashima, Y; Kinami, J; Nagatomo, T Characteristics of 125I-iodocyanopindolol binding to beta-adrenergic and serotonin-1B receptors of rat brain: selectivity of beta-adrenergic agents. Jpn J Pharmacol 52:195-200 (1990) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2
Type:
Protein
Mol. Mass.:
50486.84
Organism:
Rattus norvegicus (Rat)
Description:
P18090
Residue:
466
Sequence:
MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDDDDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
  
Inhibitor
Name:
BDBM50240370
Synonyms:
1-(2-(allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol (Oxprenolol) | 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol(oxprenolol) | CHEMBL546 | OXPRENOLOL | Trasicor
Type:
Small organic molecule
Emp. Form.:
C15H23NO3
Mol. Mass.:
265.348
SMILES:
CC(C)NCC(O)COc1ccccc1OCC=C
Structure:
Search PDB for entries with ligand similarity: