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Target
Oxytocin receptor
Ligand
BDBM81893
Substrate
n/a
Ki
4.7±n/a nM
Comments
PDSP_1042
Citation
 Pettibone, DJ; Clineschmidt, BV; Lis, EV; Reiss, DR; Totaro, JA; Woyden, CJ; Bock, MG; Freidinger, RM; Tung, RD; Veber, DF In vitro pharmacological profile of a novel structural class of oxytocin antagonists. J Pharmacol Exp Ther 256:304-8 (1991) [PubMed] 
Target
Name:
Oxytocin receptor
Synonyms:
OXTR | OXYR_MACMU | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42932.85
Organism:
Rhesus
Description:
Oxytocin OXTR Rhesus::P56494
Residue:
389
Sequence:
MEGELAANWSTEAVNSSAAPPGAEGNCTAGPPRRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRMALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGNRLGETSTSKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM81893
Synonyms:
CAS_3083084 | L-366,811 | NSC_3083084
Type:
Small organic molecule
Emp. Form.:
C43H56N8O6
Mol. Mass.:
780.9547
SMILES:
CCC(C)C(N)C(=O)N(C(Cc1c[nH]c2ccccc12)C=O)C(=O)C1CCCN1C(=O)C(CC1=CC=CCC1(C(=O)N1CCNCC1)C(=O)N1CC=CC=C1)NC |c:38,56,58,t:36|
Structure:
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