Reaction Details Report a problem with these data
Target
Norepinephrine transporter
Ligand
BDBM50073444
Substrate
n/a
Ki
3800±n/a nM
Comments
PDSP_1905
Citation
 Shank, RP; Vaught, JL; Pelley, KA; Setler, PE; McComsey, DF; Maryanoff, BE McN-5652: a highly potent inhibitor of serotonin uptake. J Pharmacol Exp Ther 247:1032-8 (1988) [PubMed] 
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
  
Inhibitor
Name:
BDBM50073444
Synonyms:
2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one | CHEMBL621 | TRAZODONE
Type:
Small organic molecule
Emp. Form.:
C19H22ClN5O
Mol. Mass.:
371.864
SMILES:
Clc1cccc(c1)N1CCN(CCCn2nc3ccccn3c2=O)CC1
Structure:
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