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TargetCCKBR
LigandBDBM50084033
Substrate/Competitorn/a
Ki 0.06±n/a nM
CommentsPDSP_2198
Citation Ito, HSogabe, HNakarai, TSato, YTomoi, MKadowaki, MMatsuo, MTokoro, KYoshida, K Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide. J Pharmacol Exp Ther268:571-5 (1994) [PubMed]
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CCKBR
Name:CCKBR
Synonyms:Cholecystokinin A
Type:Enzyme Catalytic Domain
Mol. Mass.:48683.10
Organism:GUINEA PIG
Description:Cholecystokinin A CCKBR GUINEA PIG::H0VZC5
Residue:450
Sequence:
MELLKLNRSLQGPGPGPGAPLCRPAGPLLNSSGAGNVSCETPRIRGAGTRVKSMAILFNV
TSLLSCWNKYRIIKVLGLSRRLRTVTKAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFG
TVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSG
LLMVPYPVYTAVQPVGPRVLQCVHRWPNARVRQTWSVLLLLLLFFVPGVVMAVAYGLISR
ELYLGLRFDGDADSESQSRVRGPGGLSGSAPGPAHQNGRCRPESGLSGEDSDGCYVQLPR
SRPALELSALAASTPAPGPGPRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRA
FDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARP
RPLPEEDPPTPSIASLSRLSYTTISTLGPG
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BDBM50084033
NameBDBM50084033
Synonyms:1H-Indole-2-carboxylic acid [(R)-1-(2-fluoro-phenyl)-4-oxo-3,4,6,7-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-3-yl]-amide | CHEMBL333994 | FK480
TypeSmall organic molecule
Emp. Form.C26H19FN4O2
Mol. Mass.438.4531
SMILESFc1ccccc1C1=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C(=O)N2CCc3cccc1c23 |t:8|
Structure
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n/a